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Dr. Anne-Kathrin Schultz
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Sprechzeiten/Office hours:
- Mi., 13-14 Uhr, oder nach Vereinbarung
- Themen: z.B. Statistik, Bioinformatik, Prüfungsangst, Lernmethoden
(Weiterbildung als Systemische Beraterin und in Prüfungscoaching)
Bioinformatics Network in Göttingen:
The Bioinformatics/Computational Biology groups in Göttingen- organize a joint Bioinformatics seminar (monthly)
where members of the different groups as well as invited speakers present their projects - organized the German Conference on Bioinformatics (GCB) 2013 in Göttingen
Teaching:
- Statistik für Biologiestudierende (2017)
- Algorithmen der Bioinformatik I (2016/2017)
- Bioinformatics Tutorial for Molecular Biology Students (2016/2017)
- Bioinformatics and Biostatistics Basics in the Jacob-Henle-Program for Experimental Medicine of the University Medical Center Göttingen (2016/2017)
- Angewandte Bioinformatik (2015/2016)
- Bioinformatics Tutorial for Molecular Biology Students (2012/2013)
- Bioinformatik-Praktikum für Fortgeschrittene
Research Interests:
- HIV-1 subtyping and recombination detection
- Classification of hepatitis B virus genotypes and recombinants forms
- Recombination analysis in viruses with circular genomes (e.g. HBV)
- Chimera detection in 16S rRNA sequences
Software:
- jpHMM - A jumping profile HMM to detect recombinations in genomic sequences of HIV-1 and HBV
Publications:
Papers in journals and refereed conference proceedings:-
C. Braun, A. Thürmer, R. Daniel, A.-K. Schultz, I. Bulla, H. Schirrmeier, D. Mayer, A. Neubert, C. Czerny (2017)
Genetic Variability of Myxoma Virus Genomes
Journal of Virology 2017, 91(4):e01570-16 -
I. Bulla, A.-K. Schultz, C. Chesneau, T. Mark, F. Serea (2014)
A model-based information sharing protocol for profile hidden Markov models used for HIV-1 recombination detection
BMC Bioinformatics 2014, 15:205 -
A.-K. Schultz, I. Bulla, M. Abdou-Chekaraou, E. Gordien, B. Morgenstern, F. Zoulim, P. Dény, M. Stanke (2012)
jpHMM: recombination analysis in viruses with circular genomes such as the hepatitis B virus
Nucleic Acids Research, 40 (W1), W193-W198 (pdf).
Cover Figure 2012 NAR Web Server Issue: 
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I. Bulla, A.-K. Schultz, P. Meinicke (2012)
Improving Hidden Markov Models for Classification of Human Immunodeficiency Virus-1 Subtypes through Linear Classifier Learning
Statistical Applications in Genetics and Molecular Biology: Vol. 11: Iss. 1, Article 1 -
T. Unterthiner, A.-K. Schultz, J. Bulla, B. Morgenstern, M. Stanke, I. Bulla (2011)
Detection of viral sequence fragments of HIV-1 subfamilies yet unknown
BMC Bioinformatics 2011, 12:93 -
I. Bulla, A.-K. Schultz, F. Schreiber, M. Zhang, T. Leitner, B. Korber, B. Morgenstern, M. Stanke (2010)
HIV classification using the coalescent theory
Bioinformatics, 26(11):1409-1415 (pdf). - M. Zhang, B. Foley, A.-K. Schultz, J. Macke, I. Bulla, M. Stanke, B. Morgenstern, B. Korber, T. Leitner (2010)
The role of recombination in the emergence of a complex and dynamic HIV epidemic
Retrovirology 2010, 7:25, doi:10.1186/1742-4690-7-25 -
A.-K. Schultz, M. Zhang, I. Bulla, T. Leitner, B. Korber, B. Morgenstern, M. Stanke (2009)
jpHMM: Improving the reliability of recombination prediction in HIV-1.
Nucleic Acids Research, 37 (Web Server Issue), W647 - W651 (pdf). - A.-K. Schultz, M. Zhang, T. Leitner, B. Korber,
B. Morgenstern, M. Stanke
jpHMM: Erkennung von Rekombinationen bei HIV
BIOforum 2/2008, 44-46. - A.-K. Schultz, M. Zhang, T. Leitner, C. Kuiken, B. Korber,
B. Morgenstern, M. Stanke (2006)
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
BMC Bioinformatics 7:265 (pdf). -
M. Zhang, A.-K. Schultz, C. Calef, C. Kuiken, T. Leitner,
B. Korber, B. Morgenstern, M. Stanke (2006)
jpHMM at GOBICS: a web server to detect genomic recombinations in HIV-1
Nucleic Acids Research, 34 (Web Server Issue), W463 - W465 (pdf). -
M. Zhang, A.-K. Schultz, B. Morgenstern, M. Stanke, B. Korber,
T. Leitner (2005)
Greater HIV Genome Diversities Inferred From Re-subtyping of HIV Database Sequences
Proc. German Conference on Bioinformatics (Discovery Notes, Poster Abstracts), pp 5 - 7.
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A.-K. Schultz, M. Abdou Chekaraou, I. Bulla, E. Gordien, B. Morgenstern, F. Zoulim, M. Stanke, P. Deny
A jumping profile Hidden Markov Model (jpHMM) approach to explore HBV recombination patterns indicates that HBV recombination occurs all along the genome with a high frequency in the precore/core region and defines 17 spreading recombinant forms (SRF),
2010 International Meeting on Molecular Biology of Hepatitis B Viruses, Taipei, Taiwan
Travel Grant, Hepatitis B Foundation -
A.-K. Schultz, M. Zhang, I. Bulla, T. Leitner, B. Korber, B. Morgenstern, M. Stanke
jpHMM: Improving the reliability of recombination prediction in HIV-1 (pdf),
16th International HIV Dynamics & Evolution 2009, Oxford, UK -
A.-K. Schultz, M. Zhang, I. Bulla, T. Leitner, C. Kuiken, B. Korber,
B. Morgenstern, M. Stanke
jpHMM: A jumping profile HMM to detect recombinations in HIV-1,
European Conference on Computational Biology, ECCB 2008, Cagliari, Italy -
A.-K. Schultz, M. Zhang, I. Bulla, T. Leitner, C. Kuiken, B. Korber,
B. Morgenstern, M. Stanke
jpHMM: A jumping profile HMM to predict recombinations in HIV-1,
German Conference on Bioinformatics, GCB 2008, Dresden, Germany -
A.-K. Schultz, M. Zhang, T. Leitner, C. Kuiken, B. Korber,
B. Morgenstern, M. Stanke
jpHMM: Detecting recombinations in HIV-1,
15th International HIV Dynamics & Evolution 2008, Santa Fe, USA -
A.-K. Schultz, M. Zhang, T. Leitner, C. Kuiken, B. Korber,
B. Morgenstern, M. Stanke
A Jumping Profile HMM to predict recombinations in HIV-1 sequences,
13th International Bioinformatics Workshop on Virus Evolution and Molecular Epidemiology 2007, Lisbon, Portugal -
Anne-Kathrin Schultz and Mario Stanke
A Jumping Profile HMM for Remote Protein Homology Detection (pdf),
Proceedings of the German Conference on Bioinformatics, 91-92, GCB 2004, Bielefeld, Germany
- Improvement of the jpHMM approach to recombination detection in viral genomes and its application to HIV and HBV (pdf), 2011, Universität Göttingen, Germany
- Ein springendes Profil-Hidden-Markov-Modell und Anwendungen auf Rekombinationen in viralen Genomen (pdf),
2006, Universität Göttingen, Germany