Image Matrix of Learnt Oligo Functions
The plot shows the image matrix of learnt oligo functions derived from classifer based on the Hexamer Kernel. Each of the 4096 lines shows one 6-mer function obtained from an average over 50 runs. Each of the 200 columns corresponds to a certain position with 0 indicating the position of the start codon. The function values are visualized by the color of the corresponding matrix elements. The complete matrix of function values has been scaled to yield a unit maximum which is located at the ATGAAA line at position 0. For noise reduction all matrix elements with an absolute value below 0.1 have been zeroed. In general, maxima and minima indicate discriminative features which contribute to the prediction of positive (true) and negative (false) TIS. Note, that the region of discriminative features is rather small and concentrated around the start codon on the left (upstream) side of the image.
Plots of the Hexamer Functions
The plots show functions representing the hexamers out of {AAAAAA,...TTTTTT} with the maimal/minimal peaks. Function values are plotted versus position. All values are normalised, i.e. they are relative values with respect to the global maximum over all functions which is 1.0.
nr | oligomer | peak-position | peak-value | plot |
---|---|---|---|---|
897 | ATGAAA | 0 | 1.0000 | ATGAAA-Plot |
936 | ATGGCT | 0 | 0.9213 | ATGGCT-Plot |
163 | AAGGAG | -12 | 0.7866 | AAGGAG-Plot |
649 | AGGAGA | -12 | 0.7588 | AGGAGA-Plot |
908 | ATGAGT | 0 | 0.7237 | ATGAGT-Plot |
3113 | TAAGGA | -13 | 0.6590 | TAAGGA-Plot |
933 | ATGGCA | 0 | 0.6580 | ATGGCA-Plot |
1187 | CAGGAG | -13 | 0.6544 | CAGGAG-Plot |
3897 | TTATGA | -2 | 0.6482 | TTATGA-Plot |
234 | AATGGC | -1 | 0.6221 | AATGGC-Plot |
847 | ATCATG | -3 | 0.5828 | ATCATG-Plot |
1967 | CTGGTG | -3 | -0.5655 | CTGGTG-Plot |
906 | ATGAGC | 0 | 0.5624 | ATGAGC-Plot |
1249 | CATGAA | -1 | 0.5575 | CATGAA-Plot |
652 | AGGAGT | -11 | 0.5449 | AGGAGT-Plot |
335 | ACCATG | -3 | 0.5239 | ACCATG-Plot |
950 | ATGTCC | 0 | 0.5175 | ATGTCC-Plot |
41 | AAAGGA | -13 | 0.5121 | AAAGGA-Plot |
2593 | GGAGAA | -11 | 0.5104 | GGAGAA-Plot |
3306 | TATGGC | -1 | 0.5056 | TATGGC-Plot |
3741 | TGGCTA | 1 | 0.4990 | TGGCTA-Plot |
3387 | TCATGG | -2 | 0.4837 | TCATGG-Plot |
3771 | TGGTGG | -2 | -0.4743 | TGGTGG-Plot |
1849 | CTATGA | -2 | 0.4723 | CTATGA-Plot |
15 | AAAATG | -3 | 0.4656 | AAAATG-Plot |