Burkhard Morgenstern Molecular Biology Methods Course 2006 Multiple Sequence Alignment |
WWW server for multiple alignment:
CLUSTAL W (EBI)
DIALIGN (Univ. Göttingen)
T COFFEE (CNRS)
GIBBS MOTIF SAMPLER (WADSWORTH CENTER)
Mafft (Kyoto)
ProbCons (Stanford University)
Example reference sets from BAliBASE:
Reference alignments based on 3D structure:
1r69 reference alignment
1ubi reference alignment
Conserved motif included in random sequences:
rand3
Further information:
- Review Article: Notredame (2002), Pharmacogenomics 131-144
- PPT of the lecture